| Mega Man Zero 4 | Rockman Zero 4 | Capcom | 21 April 2005 | Action > Platformer | GBA | N | N | Y | Y |
| Mega Man ZX | Rockman ZX | Capcom | 06 July 2006 | Action > Platformer | NDS | N | N | Y | Y |
| Mega Man ZX Advent | Rockman ZX Advent | Capcom | 12 July 2007 | Action | NDS | N | N | Y | Y |
| Mega Man's Soccer | Rockman's Soccer | Capcom | 25 March 1994 | Sports | SNES | N | N | N | Y |
| Mega Man: Dr. Wily's Revenge | Rockman World | Capcom | 26 July 1991 | Action > Platformer | GB | N | Y | Y | Y |
| Mega Man: The Wily Wars | Rockman: Mega World | Capcom | 21 October 1994 | Action > Platformer | GEN | Y | N | Y | Y |
| Mega SWIV | No Alternate Title | Time Warner Interactive | 1994 | Action > Shooter | GEN | N | N | Y | Y |
| Mega Turrican | No Alternate Title | Data East | 1994 | Action > Platformer | GEN | N | N | Y | N |
| Megalopolis SOS | No Alternate Title | Nisso | 1983 | Action > Shooter | MSX | N | N | Y | N |
| Megami Tensei Gaiden: Last Bible | No Alternate Title | Atlus | 22 April 1994 | Role Playing | GG | N | Y | Y | N |
| Megami Tensei Gaiden: Last Bible II | Megaten Gaiden: Last Bible II | Atlus | 19 November 1993 | Role Playing | GB | N | N | Y | Y |
| Megami Tensei Gaiden: Last Bible Special | No Alternate Title | Sega | 24 March 1995 | Role Playing | GG | N | N | Y | N |
| Megumi Rescue | No Alternate Title | Sega | 30 July 1988 | Action | SMS | N | N | Y | N |
| Meikyuu Jiin Dababa | Temple Labyrinth Dababa | Konami | 29 May 1987 | Action | FDS | N | N | Y | N |
| Meitantei Conan & Kindaichi Shounen no Jikenbou: Meguri au Futari no Meitantei | Detective Conan & Kindaichi Case Files: Chance Encounter of 2 Great Detectives | Bandai Namco | 05 February 2009 | Adventure | NDS | N | N | Y | N |
| Meitantei Conan: Karakuri Jiin Satsujin Jiken | Detective Conan: The Mechanical Temple Murder Case | Banpresto | 24 February 2000 | Adventure | GB | N | N | Y | N |
| Meitantei Conan: Kigantou Hihou Densetsu | Detective Conan: The Legendary Treasure of Strange Rock Island | Banpresto | 31 March 2000 | Adventure | GB | N | N | Y | N |
| Meitantei Holmes: M-Kara no Chousenjou | No Alternate Title | Towachiki | 01 May 1989 | Adventure | NES | N | N | N | N |
| Melpool Land | No Alternate Title | Compile | 29 May 1991 | Action | PC98 | N | N | Y | N |
| Melty Blood | No Alternate Title | Watanabe Seisakujo | 23 December 2002 | Action > Fighting | PC | N | N | Y | N |
