| Equipable Umaro | HatZen08 | Final Fantasy III | Role Playing | SNES | GP | Improvement | 1.0 | 07 Jan 2013 |
| Equipment Check Event Command | Madsiur | Final Fantasy III | Role Playing | SNES | GP, O | Improvement | 1.1 | 28 Apr 2016 |
| Equipment Progression Balance | Kethinov | Secret of Mana | Role Playing > Action RPG | SNES | GP | Improvement | 1.6 | 12 Nov 2019 |
| Ermac | Szemigi | Mortal Kombat II Special | Action > Fighting | NES | T, O | Improvement | full | 11 Dec 2018 |
| Escape From Base 57 | BMF54123 | Bomberman | Action | NES | G, L | Complete | 1.0 | 02 Nov 2002 |
| Escape From Metroid Zero | uNsane | Metroid: Zero Mission | Action > Platformer | GBA | L | Complete | 1.02 | 18 Feb 2009 |
| Escape From Planet Metroid | Sylux | Super Metroid | Action Adventure | SNES | G, L | Complete | 1.0 | 25 Aug 2012 |
| Escape from Skull Island | ChaosComposer | Super Mario Bros. 3 | Action > Platformer | NES | L, T | Complete | 1.0 | 22 Apr 2017 |
| Eternal Champions - Special Edition | BillyTime! Games | Eternal Champions | Action > Fighting | GEN | GP | Improvement | 2.3 | 28 Jul 2020 |
| Eternal Veldt | HatZen08 | Final Fantasy III | Role Playing | SNES | GP | Improvement | 1.0 | 30 Dec 2013 |
| Euro 2016 Soccer | DANGER X | Soccer | Sports | NES | G, T | Improvement | 1.0 | 02 Jul 2016 |
| European Backport Edition | Prof. 9 | The Legend of Zelda: The Minish Cap | Action Adventure | GBA | L, T, O | Bug Fix | 1.0 | 20 Dec 2013 |
| European Font Enhancement | Dragonsbrethren | Final Fantasy IV Advance | Role Playing | GBA | G | Improvement | 0.1 | 31 Aug 2006 |
| European Stripper Restoration Hack | Dragonsbrethren | Final Fantasy IV Advance | Role Playing | GBA | G | Improvement | 1.0 | 31 May 2006 |
| Even Gauge | HatZen08 | Final Fantasy III | Role Playing | SNES | GP | Improvement | 1.1d | 12 Feb 2014 |
| Everybody Gets a Chocobo | PowerPanda | Final Fantasy III | Role Playing | SNES | G | Bug Fix | 1.1 | 20 Jul 2018 |
| Evil Dead: Ash lives! | Crying Onion | Splatterhouse: Wanpaku Graffiti | Action | NES | G, T, O | Complete | 1.0 | 23 Apr 2020 |
| Evil Overload | The Komrade | Phantasy Star II | Role Playing | GEN | G, L, T, GP | Improvement | 1.02 | 21 Dec 2007 |
| Excite Mario Bros. | Yoshi | Super Mario Bros. | Action > Platformer | NES | G, S, L, T, GP | Complete | 1.0 | 01 Apr 2002 |
| Excitebike 7 maps | BZK | Vs. Excitebike | Racing | FDS | L | Improvement | 001 | 07 Oct 2016 |
